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Sebastian Seung discusses his groundbreaking work on the fly connectome and his new startup Memazing, which aims to create digital brain emulations by mapping and simulating neural connections, with the ultimate goal of understanding intelligence and potentially transcending biological constraints.
A groundbreaking startup called Hertha Metals is revolutionizing steel production in the United States by developing a cleaner, more cost-effective process that uses natural gas instead of coal, potentially reducing emissions by 50% and production costs by up to 30%.
Misha Laskin, co-founder of Reflection AI, discusses the company's mission to build frontier open intelligence, arguing that open-source AI models can compete with closed models and that the West needs to counter the rise of Chinese open-source AI technologies.
A wide-ranging discussion with Joshua Steinman about his experiences in the Navy, White House, and cybersecurity, exploring topics from Trump's intelligence to China's technological threats and the urgent need to reindustrialize and secure America's critical infrastructure.
Celine Halioua discusses her company Loyal's groundbreaking work developing a daily pill for dogs that could extend their lifespan by at least one year, with the first therapy potentially available in 2026 and the potential to pave the way for human longevity research.
Gerard Barron, CEO of The Metals Company, discusses his vision for harvesting polymetallic nodules from the ocean floor as a less environmentally destructive alternative to land-based mining for critical minerals needed for the global energy transition.
An exploration of China's engineering culture and its contrast with the United States' increasingly lawyerly approach to innovation, revealing the strengths and challenges of both nations' economic and technological development strategies.
Ashlee Vance discusses his experiences interviewing tech luminaries like Elon Musk, Brian Johnson, and Palmer Luckey, sharing insights into their personalities, work ethic, and the challenges of covering complex technological frontiers like quantum computing and fusion. He reflects on his journalistic career, highlighting the persistent and focused nature of innovators, and teases upcoming projects for his podcast Core Memory.